NFL Week 3 Predictions and Picks: Niners roll on, Chargers top Vikings, Broncos wilt to 0-3

Week 3 NFL picks and predictions against the spread, total and moneyline.

NFL picks against the spread, total and moneyline

It’s the third week of the 2023 NFL season! In this column, find a comprehensive breakdown of each and every single game, complete with free NFL picks.

New York Giants vs San Francisco 49ers

Brock Purdy and the 49ers are on a roll and with their season home opener in Week 3 of the NFL slated for Thursday Night Football, they should continue their rich vein of form at the expense of the Giants.


SU: Niners
ATS: Niners -10 (-110)
Totals: Over 43.5