NFL Week 1 Predictions and Picks: Chiefs Top Lions; Jets Stun Bills; Raiders

Week 1 NFL picks and predictions, best bets and odds

Week 1 NFL odds, best bets and NFL picks against the spread

Week 1 of the NFL is the most unpredictable of any season, with every single team brimming with optimism and hope for what is to come. It’s a clean slate – the proverbial tabula rasa – and anything is possible.

We dive into the first week of the 2023 NFL season, serving up picks and predictions for each and every single game.

Detroit Lions vs Kansas City Chiefs (-4)

Thursday, 8:20 PM ET, NBC

The Detroit Lions hope to better after a strong finish down the stretch last season. Dan Campbell is coming off his best coaching season with the Lions, Jared Goff enjoyed a somewhat redeeming campaign, Adrian Hutchinson figures to be better….and so on. But does it warrant the over-the-top hype?

Opening the season against the defending Super Bowl champions is the equivalent of drawing the short straw. Travis Kelce might be ruled out, but Patrick Mahomes will be raring to go and he’ll have plenty of weapons around him to dictate the play.

The Picks:

SU: Chiefs
ATS: Chiefs -4
Totals: Over 52.5